Hoosier Pork Tenderloin Sandwich

Crispy, golden, and utterly satisfying, the Hoosier Pork Tenderloin Sandwich is a true Midwestern classic that will win over your taste buds. This beloved Indiana staple features juicy, hand-breaded pork tenderloin, pounded thin for ultimate tenderness, then coated in a flavorful blend of seasoned flour, egg wash, and crunchy breadcrumbs. Fried to perfection in hot oil, the tenderloin develops a beautifully crisp crust that contrasts perfectly with the fluffy, lightly toasted hamburger buns. Topped with a vibrant medley of fresh lettuce, juicy tomato slices, tangy pickles, and smothered with creamy mayo and zesty mustard, this sandwich delivers bold layers of flavor in every bite. Quick and easy to prepare in under 40 minutes, it’s the ultimate comfort food for both weeknight dinners and weekend indulgence.

Nutriscore Rating: 63/100

Prep Time:20 mins

Cook Time:15 mins

Total Time:35 mins

Servings: 4

Ingredients

• 1 lb Pork tenderloin
• 1 cup All-purpose flour
• 2 Eggs
• 0.5 cup Buttermilk
• 2 tsp Salt
• 1 tsp Black pepper
• 1 tsp Garlic powder
• 1 tsp Paprika
• 1 cup Breadcrumbs
• 0.5 cup Panko breadcrumbs
• 2 cups Vegetable oil
• 4 Hamburger buns
• 4 leaves Lettuce
• 4 Tomato slices
• 4 slices Pickles
• 0.25 cup Mayonnaise
• 2 tbsp Mustard

Directions

Step 1

Trim the pork tenderloin of any excess fat and silver skin. Slice into 4 even pieces.

Step 2

Place each pork piece between two sheets of plastic wrap. Using a meat mallet or rolling pin, pound the pork pieces until they are about 1/4 inch thick.

Step 3

In a shallow dish, mix the all-purpose flour with 1 teaspoon of salt, 1/2 teaspoon of black pepper, garlic powder, and paprika.

Step 4

In another shallow bowl, whisk together the eggs and buttermilk until fully combined.

Step 5

In a third shallow dish, combine the breadcrumbs, panko breadcrumbs, and the remaining 1 teaspoon of salt and 1/2 teaspoon of black pepper.

Step 6

Dredge each piece of pork in the flour mixture, shaking off any excess, then dip into the egg mixture, and finally coat with the breadcrumb mixture. Press lightly to ensure the coating adheres.

Step 7

Heat vegetable oil in a large skillet over medium-high heat until the oil reaches 350°F (175°C). You can test the temperature by dropping in a breadcrumb—it should sizzle immediately.

Step 8

Carefully place the breaded pork pieces into the hot oil, frying in batches to avoid overcrowding. Fry for about 3-4 minutes per side, or until golden brown and fully cooked through.

Step 9

Transfer the cooked tenderloins to a paper towel-lined plate to drain any excess oil.

Step 10

Lightly toast the hamburger buns in a dry skillet or toaster.

Step 11

Assemble the sandwiches by spreading mayonnaise and mustard on each bun, then layering with the fried pork tenderloin, lettuce, tomato slices, and pickles.

Step 12

Serve immediately and enjoy the classic Hoosier Pork Tenderloin Sandwich!

Nutrition Facts

Serving size	1870.4 grams (1870.4g)

Amount per serving	% Daily Value*
Calories	6221

Total Fat 515.70g	661%
Saturated Fat 83.90g	420%
Polyunsaturated Fat 271.60g
Cholesterol 753mg	251%
Sodium 10075mg	438%
Total Carbohydrate 280.20g	102%
Dietary Fiber 68.70g	245%
Total Sugars 19.70g
Protein 218.60g	437%

Vitamin D 182IU	908%
Calcium 466mg	36%
Iron 26mg	142%
Potassium 2969mg	63%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 69.9%

Protein: 13.2%

Carbs: 16.9%