Ham Cheese Stuffed Meatloaf

Take your classic comfort food up a notch with this indulgent Ham Cheese Stuffed Meatloaf! This hearty recipe combines a perfectly seasoned blend of ground beef and pork with savory layers of sliced deli ham and gooey Swiss or cheddar cheese, rolled into a show-stopping centerpiece. A sweet and tangy glaze made with ketchup, brown sugar, and mustard adds the perfect finishing touch, caramelizing beautifully in the oven. Ideal for family dinners or special gatherings, this stuffed meatloaf is not only easy to prepare but also delivers an irresistible combination of textures and flavors in every bite. Serve it alongside mashed potatoes or a fresh green salad for a satisfying, crowd-pleasing meal!

Nutriscore Rating: 59/100

Prep Time:20 mins

Cook Time:60 mins

Total Time:80 mins

Servings: 6

Ingredients

• 2 pounds ground beef
• 0.5 pounds ground pork
• 0.75 cups plain breadcrumbs
• 0.5 cups milk
• 1 large egg
• 1 medium yellow onion, finely chopped
• 2 garlic cloves, minced
• 1 tablespoon Worcestershire sauce
• 1 teaspoon dried Italian seasoning
• 1.5 teaspoons salt
• 1 teaspoon black pepper
• 6 slices sliced deli ham
• 4 slices sliced Swiss or cheddar cheese
• 0.5 cups ketchup
• 2 tablespoons brown sugar
• 1 teaspoon yellow mustard

Directions

Step 1

Preheat your oven to 375°F (190°C). Line a baking sheet with parchment paper or lightly grease it.

Step 2

In a large mixing bowl, combine the ground beef, ground pork, breadcrumbs, milk, egg, chopped onion, minced garlic, Worcestershire sauce, Italian seasoning, salt, and black pepper. Mix gently with your hands until everything is just combined—avoid over-mixing.

Step 3

Place the meat mixture onto the prepared baking sheet, and flatten it into a rectangular shape, about 1 inch thick.

Step 4

Layer the slices of ham evenly over the meat mixture, leaving a small border around the edges. Then, add the cheese slices on top of the ham.

Step 5

Carefully roll the meatloaf into a log shape, starting from one of the shorter ends. Pinch the seams together to seal the filling inside.

Step 6

Place the meatloaf seam-side down on the baking sheet. Reshape if necessary to ensure it is even and compact.

Step 7

In a small bowl, mix the ketchup, brown sugar, and mustard to make the glaze. Spread half of the glaze evenly over the top of the meatloaf.

Step 8

Bake the meatloaf in the preheated oven for 50 minutes. After 50 minutes, spread the remaining glaze on top of the meatloaf and return it to the oven for another 10 minutes.

Step 9

Remove the meatloaf from the oven and let it rest for 10 minutes before slicing and serving.

Nutrition Facts

Serving size	1963 grams (1963.0g)

Amount per serving	% Daily Value*
Calories	4032

Total Fat 262.60g	337%
Saturated Fat 107.70g	539%
Polyunsaturated Fat 1.00g
Cholesterol 1232mg	411%
Sodium 7862mg	342%
Total Carbohydrate 135.40g	49%
Dietary Fiber 7.10g	25%
Total Sugars 57.50g
Protein 291.30g	583%

Vitamin D 159IU	795%
Calcium 1377mg	106%
Iron 25mg	141%
Potassium 3784mg	81%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 58.1%

Protein: 28.6%

Carbs: 13.3%