Whip up a crowd-pleasing weeknight dinner or game-day snack with this Grands Pepperoni Pizza Bake! Bursting with cheesy, savory goodness, this quick and easy recipe combines the irresistible flavors of classic pizza with fluffy Pillsbury Grands biscuits for a pull-apart casserole everyone will love. Perfectly seasoned with Italian herbs, melty mozzarella, zesty pizza sauce, and a generous topping of crispy pepperoni, this dish is ready in just 35 minutes from start to finish. Customize it with your favorite veggies like bell peppers or mushrooms for added flair, and enjoy a hassle-free meal that’s guaranteed to satisfy. Perfect for family dinners, potlucks, or a cozy night in, this one-pan pizza bake is your new go-to comfort food favorite!
Preheat your oven to 375°F (190°C) and lightly grease a 9x13-inch baking dish with non-stick spray or olive oil.
Cut each Pillsbury Grands biscuit into quarters, then place them in a large mixing bowl.
Pour 1 tablespoon of olive oil and the pizza sauce over the biscuit pieces. Mix gently to coat them evenly.
Add 1 1/2 cups of shredded mozzarella cheese, 1/2 cup of pepperoni slices, and any optional toppings. Sprinkle with Italian seasoning and stir until combined.
Transfer the biscuit mixture to the prepared 9x13-inch baking dish, spreading it out into an even layer.
Sprinkle the remaining 1/2 cup of mozzarella cheese, 1/4 cup of grated Parmesan, and the rest of the pepperoni slices evenly over the top.
Bake in the preheated oven for 20-25 minutes, or until the biscuits are golden and cooked through, and the cheese is melted and bubbly.
Remove from the oven and let cool for 5 minutes before serving. Garnish with additional Parmesan or fresh basil, if desired.
Serving size | 853.2 grams (853.2g) |
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Amount per serving | % Daily Value* |
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Calories | 2441 |
Total Fat 182.30g | 234% |
Saturated Fat 76.10g | 381% |
Polyunsaturated Fat 1.30g | |
Cholesterol 435mg | 145% |
Sodium 8258mg | 359% |
Total Carbohydrate 72.10g | 26% |
Dietary Fiber 10.50g | 38% |
Total Sugars 22.80g | |
Protein 123.00g | 246% |
Vitamin D 0IU | 0% |
Calcium 2042mg | 157% |
Iron 11mg | 63% |
Potassium 2382mg | 51% |
Source of Calories