Buttery Chicken Casserole

Cozy up with a warm, comforting dish of Buttery Chicken Casserole—a rich and satisfying meal that's perfect for busy weeknights or family dinners. This hearty casserole starts with tender, lightly-seared chicken breasts seasoned with garlic and black pepper, nestled in a creamy, cheesy sauce made from a luscious blend of butter, flour, chicken broth, and heavy cream. Packed with colorful mixed vegetables and topped with a golden, fluffy Bisquick crust, each bite offers the perfect balance of flavors and textures. Ready in just about an hour, this one-dish wonder combines convenience with irresistible homemade taste, making it a crowd-pleaser for all. Pair it with a crisp green salad or your favorite side for a wholesome, indulgent dinner your family will request on repeat!

Nutriscore Rating: 62/100

Prep Time:20 mins

Cook Time:40 mins

Total Time:60 mins

Servings: 6

Ingredients

• 4 pieces Boneless, skinless chicken breasts
• 1 teaspoon Salt
• 0.5 teaspoon Black pepper
• 1 teaspoon Garlic powder
• 6 tablespoons Butter
• 2 tablespoons All-purpose flour
• 2 cups Chicken broth
• 1 cup Heavy cream
• 1.5 cups Shredded cheddar cheese
• 2 cups Frozen mixed vegetables
• 1.5 cups Bisquick mix or similar
• 1 cup Whole milk

Directions

Step 1

Preheat your oven to 375°F (190°C) and grease a 9x13-inch baking dish.

Step 2

Season the chicken breasts with salt, black pepper, and garlic powder. Set aside.

Step 3

In a large skillet, melt 2 tablespoons of butter over medium heat. Add the chicken breasts and cook for 3-4 minutes per side until lightly browned (they don’t need to be fully cooked). Remove the chicken and set aside.

Step 4

In the same skillet, melt the remaining 4 tablespoons of butter. Add the flour and whisk continuously for about 1-2 minutes to create a roux.

Step 5

Slowly add the chicken broth while whisking, ensuring no lumps form. Cook for 2-3 minutes until slightly thickened.

Step 6

Stir in the heavy cream and shredded cheddar cheese, whisking until the cheese is fully melted and the sauce is smooth.

Step 7

Add the frozen mixed vegetables to the sauce and stir to combine.

Step 8

Spread the vegetable-cheese mixture evenly in the prepared baking dish.

Step 9

Place the seared chicken breasts on top of the vegetable mixture.

Step 10

In a separate bowl, combine the Bisquick mix and whole milk, stirring until a smooth batter forms.

Step 11

Pour the batter over the chicken and vegetable mixture, spreading it evenly to create a crust.

Step 12

Bake in the preheated oven for 35-40 minutes, or until the top is golden and bubbly.

Step 13

Remove from the oven and let the casserole rest for 5 minutes before serving.

Nutrition Facts

Serving size	2418.8 grams (2418.8g)

Amount per serving	% Daily Value*
Calories	4417

Total Fat 255.30g	327%
Saturated Fat 137.70g	689%
Polyunsaturated Fat 2.40g
Cholesterol 1240mg	413%
Sodium 7954mg	346%
Total Carbohydrate 205.60g	75%
Dietary Fiber 18.70g	67%
Total Sugars 41.90g
Protein 297.00g	594%

Vitamin D 128IU	639%
Calcium 2136mg	164%
Iron 19mg	104%
Potassium 3503mg	75%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 53.3%

Protein: 27.6%

Carbs: 19.1%